The work of Chicome Itzcuintli Amatlapalli explores Mexican and Mesoamerican indigeneity, cultural identity, and issues of decolonization. He explores in his work indigenous spirituality, metaphysics, and history, as well as the traumas of colonisation and cultural erasure. His paintings in oil, done in a style reminiscent of Colonial and baroque European art, merge both European and Indigenous traditions. The paintings, which suggest the images of virgins and saints found in Mexican Colonial churches but which depict prehispanic gods and ideas, present, in terms understandable to any Latin-American, the idea that indigenous spirituality is as worthy of representation as the imposed Catholic faith. They imagine a past in which indigenous concepts were given respect and importance, and a present in which neither our Spanish nor Indigenous heritages are denied, but are rather embraced and understood as mutually forming us. His paintings take seriously indigenous concepts and world-views, in order to open up vistas and understandings which are the heritage of modern Mesoamericans and Chicanos. In his work, C. I. Amatlapalli hopes to inspire new visions of ancient wisdom.